Satb2^{tm1.1(cre/GFP)Rpa}
Targeted Allele Detail

Summary

• Symbol: Satb2^{tm1.1(cre/GFP)Rpa}
• Name: special AT-rich sequence binding protein 2; targeted mutation 1.1, Richard D Palmiter
• MGI ID: MGI:5896327
• Synonyms: Satb2^Cre
• Gene: Satb2 Location: Chr1:56833140-57017809 bp, - strand Genetic Position: Chr1, 28.72 cM
• Alliance: Satb2^{tm1.1(cre/GFP)Rpa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301067
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Satb2^{tm1.1(cre/GFP)Rpa} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Satb2 (MGI:2679336)

• Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just after the termination codon of the mouse Statb2 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977, J:301067)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Satb2 (mouse) Summary of all recombinase alleles driven by Satb2. Comparative matrix view of recombinase activities Alliance mouse Satb2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Satb2 Mutation: 43 strains or lines available

References

• Original: J:301067 Jarvie BC, et al., Satb2 neurons in the parabrachial nucleus mediate taste perception. Nat Commun. 2021 Jan 11;12(1):224
• All: 4 reference(s)