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Pde6aem1(IMPC)Mbp
Endonuclease-mediated Allele Detail
Summary
Symbol: Pde6aem1(IMPC)Mbp
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI ID: MGI:5896441
Gene: Pde6a  Location: Chr18:61353387-61422995 bp, + strand  Genetic Position: Chr18, 34.41 cM
Alliance: Pde6aem1(IMPC)Mbp page
IMPC: Pde6a gene page
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 6 and flanking splicing regions were constitutively deleted from the Pde6a gene using CRISPR/Cas9 gene editing technology in mouse zygotes. (J:94077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pde6a Mutation:  52 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory