Tg(Afp-ADA)#Xiay
Transgene Detail

Summary

• Symbol: Tg(Afp-ADA)#Xiay
• Name: transgene insertion, Yang Xia
• MGI ID: MGI:5897389
• Synonyms: fLi-Tg
• Transgene: Tg(Afp-ADA)#Xiay Location: unknown
• Alliance: Tg(Afp-ADA)#Xiay page

Transgene origin

• Strain of Origin: (C57BL/6J x C3H/HeJ)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Afp-ADA)#Xiay expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ADA (100)

  Ada	(MGI:87916)

• Mutation details: The 3.2-kb mouse alpha-fetoprotein promoter, containing enhancer I, drives the expression of a 1.5 kb human ADA cDNA in the fetal liver. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:234143)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:234143 Iriyama T, et al., Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia. Circulation. 2015 Feb 24;131(8):730-41
• All: 1 reference(s)