Tprn^em1Pghu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tprn^em1Pghu
• Name: taperin; endonuclease-mediated mutation 1, Peng Hu
• MGI ID: MGI:5897817
• Gene: Tprn Location: Chr2:25152630-25159897 bp, + strand Genetic Position: Chr2, 17.11 cM
• Alliance: Tprn^em1Pghu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN technology induced a 1 bp deletion in exon 1. (J:240563)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tprn Mutation: 19 strains or lines available

References

• Original: J:240563 Chen M, et al., Progressive hearing loss and degeneration of hair cell stereocilia in taperin gene knockout mice. Biochem Biophys Res Commun. 2016 Oct 28;479(4):703-707
• All: 1 reference(s)