Tg(Otp-cre)1Hzo
Transgene Detail

Summary

• Symbol: Tg(Otp-cre)1Hzo
• Name: transgene insertion 1, Huda Y Zoghbi
• MGI ID: MGI:5897831
• Synonyms: Otp-cre
• Transgene: Tg(Otp-cre)1Hzo Location: unknown
• Alliance: Tg(Otp-cre)1Hzo page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Otp-cre)1Hzo expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Otp (MGI:99835)

• Mutation details: BAC RP24-337G4 containing the Otp locus was modified by recombineering to replace the Otp coding sequence with a Cre-recombinase. This BAC also incorporates exons 2-4 of the Tbca gene; no other genes are incorporated. This modified BAC was microinjected into fertilized oocytes. (J:240674)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Otp (mouse) Summary of all recombinase alleles driven by Otp. Alliance mouse Otp gene page

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:240674 Lu HC, et al., Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr;49(4):527-536
• All: 2 reference(s)