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Ola1tm1.2Zshi
Targeted Allele Detail
Summary
Symbol: Ola1tm1.2Zshi
Name: Obg-like ATPase 1; targeted mutation 1.2, Zheng-Zheng Shi
MGI ID: MGI:5898257
Gene: Ola1  Location: Chr2:72923145-73044791 bp, - strand  Genetic Position: Chr2, 43.35 cM, cytoband C3
Alliance: Ola1tm1.2Zshi page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:236306
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector was designed to insert a single loxP site upstream of exon 2, and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 2 of the gene. Recombinase mediated recombination removed the FRT-flanked neo cassette and exon 2. (J:236306)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ola1 Mutation:  33 strains or lines available
References
Original:  J:236306 Ding Z, et al., OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression. Mol Cell Biol. 2016 Oct 15;36(20):2568-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory