Mahl^129S1/SvImJ
QTL Variant Detail

Summary

• QTL variant: Mahl^129S1/SvImJ
• Name: modifier of age related hearing loss; 129S1/SvImJ
• MGI ID: MGI:5898321
• QTL: Mahl Location: unknown Genetic Position: Chr10, Syntenic

Variant origin

• Strain of Specimen: 129S1/SvImJ

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: In the homozygous state this allele intensifies the hair cell loss and hearing loss caused by the age related hearing loss mutation on the 129S1 background (J:241137)
• Inheritance: Recessive

References

• Original: J:241137 Johnson KR, et al., Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains. Sci Rep. 2017 Mar 13;7:44450
• All: 1 reference(s)