Grk1^tvrm207
Chemically induced Allele Detail

Summary

• Symbol: Grk1^tvrm207
• Name: G protein-coupled receptor kinase 1; translational research vision model 207
• MGI ID: MGI:5902745
• Gene: Grk1 Location: Chr8:13455081-13471951 bp, + strand Genetic Position: Chr8, 5.93 cM, cytoband A2
• Alliance: Grk1^tvrm207 page

Mutation origin

• Strain of Origin: B6.Cg-Crb1^rd8/Pjn

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: This ENU induced T to C point substitution at c.1088 is predicted to cause a leucine to proline change at amino acid 363. (J:241495)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grk1 Mutation: 32 strains or lines available

References

• Original: J:241495 Charette JR, et al., A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects. Adv Exp Med Biol. 2016;854:177-83
• All: 2 reference(s)