Mirc37^tm1Boet
Targeted Allele Detail

Summary

• Symbol: Mirc37^tm1Boet
• Name: microRNA cluster 37, including Mir133b through Mir206; targeted mutation 1, Thomas Boettger
• MGI ID: MGI:5902976
• Gene: Mirc37 Location: Chr1:20749234-20753111 bp Genetic Position: Chr1, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241493
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mirc37^tm1Boet involves 3 genes/genome features (Lincmd1, Mir206, Mir133b) View all
• Mutation details: A neomycin resistance cassette with a lacZ gene replaced the sequence. This strategy removes Mir206, Mir133b and the last exon of Lincmd1 including the putative miR-133a/b binding site in Lincmd1. No beta-galactosidase expression was detected. (J:241493)

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc37 Mutation: 0 strains or lines available

References

• Original: J:241493 Boettger T, et al., The miR-206/133b cluster is dispensable for development, survival and regeneration of skeletal muscle. Skelet Muscle. 2014;4(1):23
• All: 2 reference(s)