Cxcr5^tm1.1Namt
Targeted Allele Detail

Summary

• Symbol: Cxcr5^tm1.1Namt
• Name: C-X-C motif chemokine receptor 5; targeted mutation 1.1, Neil A Mabbott
• MGI ID: MGI:5903012
• Synonyms: CXCR5^F, CXCR5F
• Gene: Cxcr5 Location: Chr9:44423084-44437741 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Cxcr5^tm1.1Namt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241561
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites were introduced into intron 1 and exon 2. Flp-mediated recombination removed the 5' FRT-flanked selection cassette and left exon 2 floxed. (J:241561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcr5 Mutation: 28 strains or lines available

References

• Original: J:241561 Bradford BM, et al., Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells. J Virol. 2017 May 15;91(10)
• All: 8 reference(s)