Tg(Myh6-Rab1a)lowGwd
Transgene Detail

Summary

• Symbol: Tg(Myh6-Rab1a)lowGwd
• Name: transgene insertion low, Gerald W Dorn II
• MGI ID: MGI:5904948
• Synonyms: Rab1low
• Transgene: Tg(Myh6-Rab1a)lowGwd Location: unknown
• Alliance: Tg(Myh6-Rab1a)lowGwd page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-Rab1a)lowGwd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rab1a (MGI:97842)

• Mutation details: The mouse Rab1a coding region including 28 bp of 5UTR and 785 bp of 3UTR is under the control of the mouse alpha-myosin heavy chain promoter. This line has transgene copy number of 5. Western blot analysis confirmed protein expression in the heart. (J:134581)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:134581 Wu G, et al., Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy. Circ Res. 2001 Dec 7;89(12):1130-7
• All: 1 reference(s)