Fbxl3^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Fbxl3^m1Btlr
• Name: F-box and leucine-rich repeat protein 3; mutation 1, Bruce Beutler
• MGI ID: MGI:5906265
• Synonyms: delargo, Fbxl3^dlrg
• Gene: Fbxl3 Location: Chr14:103318470-103337016 bp, - strand Genetic Position: Chr14, 51.73 cM, cytoband E2.2
• Alliance: Fbxl3^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 103,089,418 (v38) on chromosome 14, or base pair 10,122 in the GenBank genomic region NC_000080. The mutation corresponds to residue 899 in the mRNA sequence NM_015822 within exon 4 of 5 total exons. The mutation results in a serine (S) to leucine (L) substitution at position 176 (S176L) in the protein. (J:264634)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxl3 Mutation: 43 strains or lines available

References

• Original: J:264634 de Groot M, et al., Mutagenetix entry for delargo. MGI Direct Data Submission. 2018
• All: 1 reference(s)