Abhd5^tm1Murm
Targeted Allele Detail

Summary

• Symbol: Abhd5^tm1Murm
• Name: abhydrolase domain containing 5; targeted mutation 1, Makoto Murakami
• MGI ID: MGI:5906416
• Gene: Abhd5 Location: Chr9:122180681-122210589 bp, + strand Genetic Position: Chr9, 73.03 cM, cytoband F4
• Alliance: Abhd5^tm1Murm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240682
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exon 1. (J:240682)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abhd5 Mutation: 20 strains or lines available

References

• Original: J:240682 Hirabayashi T, et al., PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis. Nat Commun. 2017 Mar 01;8:14609
• All: 1 reference(s)