Tet1^tuft
Spontaneous Allele Detail

Summary

• Symbol: Tet1^tuft
• Name: tet methylcytosine dioxygenase 1; tuft
• MGI ID: MGI:5906894
• Synonyms: tu
• Gene: Tet1 Location: Chr10:62640349-62723242 bp, - strand Genetic Position: Chr10, 32.48 cM
• Alliance: Tet1^tuft page

Mutation origin

• Strain of Origin: 3H1/Lznf

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Nucleotide substitutions
• Mutation details: A spontaneous mutation originally identified in 3H1 consists of a C to T point mutation in exon 11 (c.5167C>T) that results in a in-frame termination (p.R1723*). (J:242825)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	9 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tet1 Mutation: 143 strains or lines available

References

• Original: J:242827 Fong KS, et al., Craniofacial features resembling frontonasal dysplasia with a tubulonodular interhemispheric lipoma in the adult 3H1 tuft mouse. Birth Defects Res A Clin Mol Teratol. 2012 Feb;94(2):102-13
• All: 3 reference(s)