AU040320^em1Janc
Endonuclease-mediated Allele Detail

Summary

• Symbol: AU040320^em1Janc
• Name: expressed sequence AU040320; endonuclease-mediated mutation 1, Jan Carette
• MGI ID: MGI:5907241
• Synonyms: Aavr^-, Kiaa0319l^-
• Gene: AU040320 Location: Chr4:126647331-126763487 bp, + strand Genetic Position: Chr4, 60.94 cM
• Alliance: AU040320^em1Janc page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intragenic deletion, Single point mutation
• Mutation details: The gene was targeted via TALEN technology using the primer pairs 5'-TGGGAGTCAAGCCAAGTC-3' and5'-GCCAGGATATTGTTGGCAGA-3'. This mutation comprises a single-nucleotide (T) deletion at position 264 of the 4379-nucleotide GenBank cDNA sequence BC028869.1, resulting in a reading-frame shift. (J:229089)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any AU040320 Mutation: 60 strains or lines available

References

• Original: J:229089 Pillay S, et al., An essential receptor for adeno-associated virus infection. Nature. 2016 Feb 4;530(7588):108-12
• All: 3 reference(s)