E330023G01Rik^{Tn(pb-Act-RFP)1.1Zhu}
Transposon induced Allele Detail

Summary

• Symbol: E330023G01Rik^{Tn(pb-Act-RFP)1.1Zhu}
• Name: RIKEN cDNA E330023G01 gene; transposon insertion 1.1, Yuan Zhuang
• MGI ID: MGI:5907607
• Synonyms: Foxl2^PB
• Gene: E330023G01Rik Location: Chr9:98630652-98702140 bp, - strand Genetic Position: Chr9, Syntenic
• Alliance: E330023G01Rik^{Tn(pb-Act-RFP)1.1Zhu} page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Transposon induced (Reporter)
• Mutation: Transposon insertion
• Mutation details: The transposon containing an unspecified hybrid actin promoter driving expression of red fluorescent protein (RFP) flanked by piggyBac-specific left and right terminal sequences was co-injected with a piggyBac-containing transgene to mobilize the transposon. Line 1 contains a transposon insertion 160 kb upstream of the Foxl2 start site in a long range enhancer. Q RT-PCR confirmed reduced expression of Foxl2. (J:210665)

Disease models

Expression

In Mice Carrying this Mutation:	36 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any E330023G01Rik Mutation: 0 strains or lines available

References

• Original: J:210665 Shi F, et al., A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Hum Mol Genet. 2014 Jul 15;23(14):3792-800
• All: 2 reference(s)