Plekha7^tm1.1Janc
Targeted Allele Detail

Summary

• Symbol: Plekha7^tm1.1Janc
• Name: pleckstrin homology domain containing, family A member 7; targeted mutation 1.1, Jan E Carette
• MGI ID: MGI:5907899
• Gene: Plekha7 Location: Chr7:115722720-115907611 bp, - strand Genetic Position: Chr7, 61.42 cM
• Alliance: Plekha7^tm1.1Janc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227858
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 8 was replaced with a cassette containing a lox71 site, FRT flanked lacZ and neo sequences and a loxP site. Recombinase mediated recombination removed the lacZ and neo sequences. (J:227858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plekha7 Mutation: 64 strains or lines available

References

• Original: J:227858 Popov LM, et al., The adherens junctions control susceptibility to Staphylococcus aureus alpha-toxin. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14337-42
• All: 1 reference(s)