Del(7Chrna7-Fan1)1Mima
Targeted Allele Detail

Summary

• Symbol: Del(7Chrna7-Fan1)1Mima
• Name: deletion, Chr 7, Mitsuru Matsumoto 1
• MGI ID: MGI:5908016
• Gene: Del(7Chrna7-Fan1)1Mima Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227984
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(7Chrna7-Fan1)1Mima involves 9 genes/genome features (Chrna7, 4930554H23Rik, Otud7a ...) View all
• Mutation details: An approximately 1.2 Mb deletion spanning from Chrna7 to Fan1 and including the coding regions of both of these genes plus Mtmr10, Trpm1, Klf13 and Otud7a was created by Flp mediated recombination between Chrna7^tm1Mima and Fan1^tm1Mima. Expression of genes within the region is reduced in brain tissue from heterozygous mice. (J:227984)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(7Chrna7-Fan1)1Mima Mutation: 0 strains or lines available

References

• Original: J:227984 Kogan JH, et al., Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder. J Neurosci. 2015 Dec 9;35(49):16282-94
• All: 1 reference(s)