Tg(Krt10-cre/ERT2)39.28.ICSLacr
Transgene Detail

Summary

• Symbol: Tg(Krt10-cre/ERT2)39.28.ICSLacr
• Name: transgene insertion 39.28.ICS, Matthieu Lacroix
• MGI ID: MGI:5908171
• Synonyms: K10CreER^T2
• Transgene: Tg(Krt10-cre/ERT2)39.28.ICSLacr Location: unknown
• Alliance: Tg(Krt10-cre/ERT2)39.28.ICSLacr page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Krt10-cre/ERT2)39.28.ICSLacr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Krt10 (MGI:96685)

• Mutation details: The modified BAC RP23-336D20 that expresses a tamoxifen-inducible Cre recombinase under the control of the Krt10 promoter was injected into a pronucleus of the FVB/N embryo to generated transgenic mice. Line 39.28.ICS was generated and used in the original reference. (J:238348)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt10 (mouse) Summary of all recombinase alleles driven by Krt10. Alliance mouse Krt10 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:238348 Goguet-Rubio P, et al., E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):11004-9
• All: 1 reference(s)