Gng8^{tm1.1(cre)Irod}
Targeted Allele Detail

Summary

• Symbol: Gng8^{tm1.1(cre)Irod}
• Name: guanine nucleotide binding protein (G protein), gamma 8; targeted mutation 1.1, Ivan Rodriguez
• MGI ID: MGI:5908376
• Synonyms: Gng8^cre
• Gene: Gng8 Location: Chr7:16625711-16629361 bp, + strand Genetic Position: Chr7, 9.15 cM
• Alliance: Gng8^{tm1.1(cre)Irod} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237342
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Gng8^{tm1.1(cre)Irod} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gng8 (MGI:109163)

• Mutation details: An IRES-cre with an FRT-flanked neo cassette was inserted into downstream of the coding region of Gng8 gene in ES cell by homologous recombination. To remove the neo cassette, mice were bred to Flp deleter mice. (J:237342)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gng8 (mouse) Summary of all recombinase alleles driven by Gng8. Comparative matrix view of recombinase activities Alliance mouse Gng8 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gng8 Mutation: 10 strains or lines available

References

• Original: J:237342 Assens A, et al., Alteration of Nrp1 signaling at different stages of olfactory neuron maturation promotes glomerular shifts along distinct axes in the olfactory bulb. Development. 2016 Oct 15;143(20):3817-3825
• All: 1 reference(s)