Mgst2^{Gt(OST22210)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Mgst2^{Gt(OST22210)Lex}
• Name: microsomal glutathione S-transferase 2; gene trap OST22210, Lexicon Genetics
• MGI ID: MGI:5908940
• Gene: Mgst2 Location: Chr3:51567781-51590098 bp, + strand Genetic Position: Chr3, 22.52 cM
• Alliance: Mgst2^{Gt(OST22210)Lex} page

Mutation origin

• Mutant Cell Line: OST22210
• Germline Transmission: Earliest citation of germline transmission: J:228296
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Insertion of a gene trap vector disrupts the gene. (J:228296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mgst2 Mutation: 10 strains or lines available

Notes

This Lexicon Genetics gene trap mutation was generated in either Lex-1 or Lex-2 (129S5/SvEvBrd) parental ES cell line. The specific ES cell line in which this mutation was made is not specified.

References

• Original: J:228296 Dvash E, et al., Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun. 2015;6:10112
• All: 1 reference(s)