Tg(TcraB5,TcrbB5)#Jlh
Transgene Detail

Summary

• Symbol: Tg(TcraB5,TcrbB5)#Jlh
• Name: transgene insertion, Jean Langhorne
• MGI ID: MGI:5909245
• Synonyms: B5 TCR
• Transgene: Tg(TcraB5,TcrbB5)#Jlh Location: unknown
• Alliance: Tg(TcraB5,TcrbB5)#Jlh page

Transgene origin

• Strain of Origin: (BALB/c x (CBA x C57BL/6))F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains contains the pre-rearranged Tcra and Tcrb from a hybridoma cell line specific for Plasmodium chabaudi MSP-1 (amino acids 1151-1171) in the context of I-E^d. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:118494)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:118494 Stephens R, et al., Malaria-specific transgenic CD4(+) T cells protect immunodeficient mice from lethal infection and demonstrate requirement for a protective threshold of antibody production for parasite clearance. Blood. 2005 Sep 1;106(5):1676-84
• All: 1 reference(s)