Bcas2^tm1.1Lil
Targeted Allele Detail

Summary

• Symbol: Bcas2^tm1.1Lil
• Name: BCAS2 pre-mRNA processing factor; targeted mutation 1.1, Lei Li
• MGI ID: MGI:5909974
• Synonyms: Bcas2^F, Bcas2^floxed, Bcas2^loxp
• Gene: Bcas2 Location: Chr3:103078971-103086479 bp, + strand Genetic Position: Chr3, 45.25 cM
• Alliance: Bcas2^tm1.1Lil page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239876
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT- and loxP-flanked neomycin resistance cassette was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and left exons 3 and 4 floxed. (J:239876)

Expression

In Mice Carrying this Mutation:	46 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcas2 Mutation: 14 strains or lines available

References

• Original: J:239876 Xu Q, et al., Maternal BCAS2 protects genomic integrity in mouse early embryonic development. Development. 2015 Nov 15;142(22):3943-53
• All: 4 reference(s)