Tg(Sox1-icre/ERT2)#Cruh
Transgene Detail

Summary

• Symbol: Tg(Sox1-icre/ERT2)#Cruh
• Name: transgene insertion, Christiana Ruhrberg
• MGI ID: MGI:5909999
• Synonyms: Sox1-iCreER^T2
• Transgene: Tg(Sox1-icre/ERT2)#Cruh Location: unknown
• Alliance: Tg(Sox1-icre/ERT2)#Cruh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Sox1-icre/ERT2)#Cruh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sox1 (MGI:98357)

• Mutation details: A 197kb mouse genomic PAC clone (RPCI21 502 p07) spanning 94 kb upstream and 103 kb downstream of Sox1 was modified by replacing the coding sequence with an inducible improved cre recombinase gene (icre/ERT2), polyadenylation sequence. No founder line information was provided. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:238839)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox1 (mouse) Summary of all recombinase alleles driven by Sox1. Alliance mouse Sox1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:238839 Tata M, et al., Regulation of embryonic neurogenesis by germinal zone vasculature. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13414-13419
• All: 1 reference(s)