Tfap2b^tm2Will
Targeted Allele Detail

Summary

• Symbol: Tfap2b^tm2Will
• Name: transcription factor AP-2 beta; targeted mutation 2, Trevor Williams
• MGI ID: MGI:5910580
• Synonyms: Tfap2b^fl
• Gene: Tfap2b Location: Chr1:19279138-19308800 bp, + strand Genetic Position: Chr1, 6.19 cM, cytoband A2-A4
• Alliance: Tfap2b^tm2Will page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:242073
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted into introns of the gene to create a conditional-ready allele. (J:270530)

Disease models

Expression

In Mice Carrying this Mutation:	22 assay results 5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfap2b Mutation: 29 strains or lines available

References

• Original: J:242073 Seberg HE, et al., TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PLoS Genet. 2017 Mar;13(3):e1006636
• All: 11 reference(s)