Rhot1^tm2.1Jmsu
Targeted Allele Detail

Summary

• Symbol: Rhot1^tm2.1Jmsu
• Name: ras homolog family member T1; targeted mutation 2.1, Janet M Shaw
• MGI ID: MGI:5910803
• Synonyms: Miro1^F
• Gene: Rhot1 Location: Chr11:80099845-80158733 bp, + strand Genetic Position: Chr11, 47.62 cM, cytoband B5
• Alliance: Rhot1^tm2.1Jmsu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site, FRT-flanked neomycin resistance gene, exon 2, and a loxP site replaced exon 2. The FRT-flanked neomycin resistance gene was removed via Flp-mediated recombination leaving exon 2 flanked by loxP sites. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rhot1 Mutation: 44 strains or lines available

Notes

The ES cell used to generate this allele was derived from a C57BL/6 mouse whereas that used to generate the tm1Jmsu allele was from a segregating B6;129 background. The same construct was used in both targeted alleles.

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 5 reference(s)