Yme1l1^tm1.1Tlan
Targeted Allele Detail

Summary

• Symbol: Yme1l1^tm1.1Tlan
• Name: YME1-like 1 (S. cerevisiae); targeted mutation 1.1, Thomas Langer
• MGI ID: MGI:5911072
• Synonyms: Yme1l^-
• Gene: Yme1l1 Location: Chr2:23046517-23089272 bp, + strand Genetic Position: Chr2, 15.24 cM
• Alliance: Yme1l1^tm1.1Tlan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229455
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 3 was deleted via cre-mediated recombination of flanking loxP sites in the germline. (J:229455)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yme1l1 Mutation: 59 strains or lines available

References

• Original: J:229455 Wai T, et al., Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice. Science. 2015 Dec 4;350(6265):aad0116
• All: 1 reference(s)