Rexo5^em1Embrp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rexo5^em1Embrp
• Name: RNA exonuclease 5; endonuclease-mediated mutation 1, Ramesh Pillai
• MGI ID: MGI:5911539
• Gene: Rexo5 Location: Chr7:119393229-119448166 bp, + strand Genetic Position: Chr7, 64.21 cM, cytoband F3
• Alliance: Rexo5^em1Embrp page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 23 bp out-of-frame deletion in exon 6. (J:243740)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rexo5 Mutation: 36 strains or lines available

References

• Original: J:243740 Silva S, et al., Characterization of the mammalian RNA exonuclease 5/NEF-sp as a testis-specific nuclear 3' --> 5' exoribonuclease. RNA. 2017 Sep;23(9):1385-1392
• All: 1 reference(s)