Ythdc2^ketu
Chemically induced Allele Detail

Summary

• Symbol: Ythdc2^ketu
• Name: YTH domain containing 2; ketu
• MGI ID: MGI:5911552
• Gene: Ythdc2 Location: Chr18:44961521-45022782 bp, + strand Genetic Position: Chr18, 23.81 cM
• Alliance: Ythdc2^ketu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis resulted in an A to G transition in exon 6 that results in the amino acid substitution of argininge for histidine at position 327 (H327R). (J:256276)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ythdc2 Mutation: 60 strains or lines available

References

• Original: J:256276 Jain D, et al., ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2. Elife. 2018 Jan 23;7:e30919
• All: 1 reference(s)