Ythdc2^em1Sky
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ythdc2^em1Sky
• Name: YTH domain containing 2; endonuclease-mediated mutation 1, Scott Keeney
• MGI ID: MGI:5911553
• Synonyms: Ythdc2^em1
• Gene: Ythdc2 Location: Chr18:44961521-45022782 bp, + strand Genetic Position: Chr18, 23.81 cM
• Alliance: Ythdc2^em1Sky page

Mutation origin

• Strain of Origin: CBA x C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted 5 base pairs in exon 6. (J:256276)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ythdc2 Mutation: 60 strains or lines available

References

• Original: J:256276 Jain D, et al., ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2. Elife. 2018 Jan 23;7:e30919
• All: 2 reference(s)