Tg(Thy1-tTA)6Lmit
Transgene Detail

Summary

• Symbol: Tg(Thy1-tTA)6Lmit
• Name: transgene insertion 6, Lars M Ittner
• MGI ID: MGI:5922013
• Synonyms: mThy1.2-tTA(6), Thy-OFF6
• Transgene: Tg(Thy1-tTA)6Lmit Location: unknown
• Alliance: Tg(Thy1-tTA)6Lmit page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The transgene comprises the neuronal specific mouse promoter, the tetracycline transactivator cDNA and poly(A) features. The transgene construct was microinjected into the proneclei of C57BL/6 zygotes. Two lines, this line and number 15, were selected for further study. The two lines display a different neuronal expression pattern in the brain. Transgenic mice appear normal. (J:213543)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:213543 Delerue F, et al., Inducible, tightly regulated and non-leaky neuronal gene expression in mice. Transgenic Res. 2014 Apr;23(2):225-33
• All: 6 reference(s)