Gpr153^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr153^em1(IMPC)J
• Name: G protein-coupled receptor 153; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5927713
• Gene: Gpr153 Location: Chr4:152358689-152369794 bp, + strand Genetic Position: Chr4, 83.0 cM
• Alliance: Gpr153^em1(IMPC)J page
• IMPC: Gpr153 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GTGTCCCTGTCCCTCTCACG, CATAGTCTGGGGCTACTGGG, GGGAACACTGAGTTGGCATA and CTAGAAGCCACATCCCTGAG, which resulted in a 1029 bp deletion beginning at Chromosome 4 positive strand position 152,279,522 bp and ending after 152,280,550 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000398729 (exon 3) and 599 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 119 and early truncation 1 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gpr153 Mutation: 28 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)