Tgfb1i1^tm1.2Cet
Targeted Allele Detail

Summary

• Symbol: Tgfb1i1^tm1.2Cet
• Name: transforming growth factor beta 1 induced transcript 1; targeted mutation 1.2. Christopher E Turner
• MGI ID: MGI:6093696
• Synonyms: Hic-5^-
• Gene: Tgfb1i1 Location: Chr7:127845963-127852884 bp, + strand Genetic Position: Chr7, 70.07 cM, cytoband F1-F3
• Alliance: Tgfb1i1^tm1.2Cet page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241234
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6 x 129S/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• LoxP flanked exons 2-7 were removed via cre-mediated recombination in the germline. (J:241234)

Expression

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tgfb1i1 Mutation: 23 strains or lines available

References

• Original: J:241234 Goreczny GJ, et al., Hic-5 remodeling of the stromal matrix promotes breast tumor progression. Oncogene. 2017 May 11;36(19):2693-2703
• All: 2 reference(s)