Rplp1^tm1.2Melt
Targeted Allele Detail

Summary

• Symbol: Rplp1^tm1.2Melt
• Name: ribosomal protein lateral stalk subunit P1; targeted mutation 1.1, Matilde E Lleonart
• MGI ID: MGI:6094830
• Synonyms: Rplp1^delta
• Gene: Rplp1 Location: Chr9:61820565-61821792 bp, - strand Genetic Position: Chr9, 33.5 cM
• Alliance: Rplp1^tm1.2Melt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218949
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 1 through 3 floxed. (J:218949)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rplp1 Mutation: 7 strains or lines available

References

• Original: J:218949 Perucho L, et al., RPLP1, a crucial ribosomal protein for embryonic development of the nervous system. PLoS One. 2014;9(6):e99956
• All: 1 reference(s)