Fam161a^{tm1(GFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Fam161a^{tm1(GFP/cre/ERT2)Wtsi}
• Name: family with sequence similarity 161, member A; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6095189
• Synonyms: tm1(EGFP_CreERT2)Wtsi
• Gene: Fam161a Location: Chr11:22957531-22980788 bp, + strand Genetic Position: Chr11, 14.25 cM, cytoband A3.3
• Alliance: Fam161a^{tm1(GFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0108_1_D09
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Conditional ready, Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Fam161a^{tm1(GFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fam161a (MGI:1921123)

• Mutation details: According to the vector molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, a Rox-flanked puromycin resistance cassette followed by one loxP site all inserted into the intron just upstream of exon 4, and a single loxP site just downstream of exon 4. (J:188991)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fam161a (mouse) Summary of all recombinase alleles driven by Fam161a. Alliance mouse Fam161a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam161a Mutation: 32 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)