Gsdma2^{tm1(GFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Gsdma2^{tm1(GFP/cre/ERT2)Wtsi}
• Name: gasdermin A2; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:6095194
• Synonyms: tm1(EGFP_CreERT2)Wtsi
• Gene: Gsdma2 Location: Chr11:98537585-98548790 bp, + strand Genetic Position: Chr11, 62.28 cM, cytoband D
• Alliance: Gsdma2^{tm1(GFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0108_3_C09
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Conditional ready, Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Gsdma2^{tm1(GFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gsdma2 (MGI:1921490)

• Mutation details: According to the vector molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, a Rox-flanked puromycin resistance cassette followed by one loxP site all inserted into the intron just upstream of exon 5, and a single loxP site downstream of exon 7. (J:188991)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gsdma2 (mouse) Summary of all recombinase alleles driven by Gsdma2. Alliance mouse Gsdma2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsdma2 Mutation: 31 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)