Tg(Fabp4-FOXC2)ASven
Transgene Detail

Summary

• Symbol: Tg(Fabp4-FOXC2)ASven
• Name: transgene insertion A, Sven Enerback
• MGI ID: MGI:6101512
• Synonyms: FOXC2 tg-A
• Transgene: Tg(Fabp4-FOXC2)ASven Location: unknown
• Alliance: Tg(Fabp4-FOXC2)ASven page

Transgene origin

• Strain of Origin: C57BL/6J x CBA

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-FOXC2)ASven expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FOXC2 (2303)

  Foxc2

  (MGI:1347481)

• Mutation details: The transgene contains the mouse promoter driving adipose-specific expression of the human cDNA. Lines A (high expression levels), B (low expression levels) and C (moderate expression levels) were generated. (J:94144)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:94144 Cederberg A, et al., FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cell. 2001 Sep 7;106(5):563-73
• All: 3 reference(s)