Myo16^tm1Tya
Targeted Allele Detail

Summary

• Symbol: Myo16^tm1Tya
• Name: myosin XVI; targeted mutation 1, Tadashi Yamamoto
• MGI ID: MGI:6107633
• Synonyms: Nyap3 KO
• Gene: Myo16 Location: Chr8:10203911-10684742 bp, + strand Genetic Position: Chr8, 4.77 cM
• Alliance: Myo16^tm1Tya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180006
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The genomic sequence that includes sequence for exon 13, encoding a lysine residue in the myosin motor domain that binds ATP, was replaced with a neomycin resistance gene cassette. (J:180006)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Myo16 Mutation: 95 strains or lines available

References

• Original: J:180006 Yokoyama K, et al., NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54
• All: 1 reference(s)