Lrrc26^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Lrrc26^{tm1.1(KOMP)Vlcg}
• Name: leucine rich repeat containing 26; targeted mutation 1.1, Velocigene
• MGI ID: MGI:6107883
• Gene: Lrrc26 Location: Chr2:25179927-25181192 bp, + strand Genetic Position: Chr2, 17.14 cM
• Alliance: Lrrc26^{tm1.1(KOMP)Vlcg} page
• IMPC: Lrrc26 gene page

Mutation origin

• Mutant Cell Line: 10167A-D5
• Germline Transmission: Earliest citation of germline transmission: J:242233
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: A 1089-bp DNA fragment between nucleotides 25,289,972-25,291,060 on Chromosome 2 (Genome Build 38) containing the entire protein coding sequence was replaced by the ZEN-UB1 cassette, which contains the E. coli galactosidase gene (lacZ) and a loxP-flanked sequence comprising the promoter of the human ubiquitin C gene driving expression of neomycin phosphotransferase. The present allele was generated by Cre recombinase-mediated excision of the selection cassette. (J:136110)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lrrc26 Mutation: 13 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)