Tex19.2tm1.2Ics
Targeted Allele Detail
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Symbol: |
Tex19.2tm1.2Ics |
Name: |
testis expressed gene 19.2; targeted mutation 1.2, Mouse Clinical Institute |
MGI ID: |
MGI:6110008 |
Gene: |
Tex19.2 Location: Chr11:121007041-121009503 bp, - strand Genetic Position: Chr11, 84.96 cM, cytoband E2
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Alliance: |
Tex19.2tm1.2Ics page
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Germline Transmission: |
Earliest citation of germline transmission:
J:243444
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A lox5171 site was inserted upstream of exon 1. An F3 site flanked hygromycin resistance cassette with a 5' lox5171 site was inserted downstream of exon 3. The construct was injected into ES cells containing the Tex19.1tm2Ics allele. Flp-mediated recombination removed the hygro cassette. Cre-mediated recombination removed exons 1-3 containing the coding sequence. Western blot analysis confirmed the absence of protein expression in ES cells and testis.
(J:243444)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tex19.2 Mutation: |
10 strains or lines available
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Original: |
J:243444 Tarabay Y, et al., Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression. J Cell Sci. 2017 Apr 15;130(8):1463-1474 |
All: |
1 reference(s) |
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