Odad4^em#Omra
Endonuclease-mediated Allele Detail

Summary

• Symbol: Odad4^em#Omra
• Name: outer dynein arm complex subunit 4; endonuclease-mediated mutation, Heymut Omran
• MGI ID: MGI:6110171
• Synonyms: Odad4^em#Omra
• Gene: Odad4 Location: Chr11:100436434-100463392 bp, + strand Genetic Position: Chr11, 63.47 cM, cytoband D
• Alliance: Odad4^em#Omra page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 mediated mutation produced deletions including exons 2 and 3 of the gene. At least 2 lines were characterized (5 and 6) and data for these lines were pooled. (J:244361)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Odad4 Mutation: 45 strains or lines available

References

• Original: J:244361 Wallmeier J, et al., TTC25 Deficiency Results in Defects of the Outer Dynein Arm Docking Machinery and Primary Ciliary Dyskinesia with Left-Right Body Asymmetry Randomization. Am J Hum Genet. 2016 Aug 04;99(2):460-9
• All: 2 reference(s)