Rufy3tm1.1Migar
Targeted Allele Detail
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Symbol: |
Rufy3tm1.1Migar |
Name: |
RUN and FYVE domain containing 3; targeted mutation 1.1, Michihirio Igarashi |
MGI ID: |
MGI:6111136 |
Gene: |
Rufy3 Location: Chr5:88712899-88799251 bp, + strand Genetic Position: Chr5, 43.77 cM
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Alliance: |
Rufy3tm1.1Migar page
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Germline Transmission: |
Earliest citation of germline transmission:
J:253649
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Parent Cell Line: |
RENKA (ES Cell)
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Strain of Origin: |
C57BL/6N
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: An FRT site flanked pgk-Neo cassette and a loxP sequence were inserted 249 bp upstream of exon 3, and a second loxP sequence 269 bp downstream of exon 3. Exon 3 was subsequently deleted via Cre-mediated recombination. Western blot analysis showed that no detectable encoded protein was expressed from this allele.
(J:253649)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rufy3 Mutation: |
37 strains or lines available
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Original: |
J:253649 Honda A, et al., Rufy3 is an adapter protein for small GTPases that activates a Rac guanine nucleotide exchange factor to control neuronal polarity. J Biol Chem. 2017 Dec 22;292(51):20936-20946 |
All: |
1 reference(s) |
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