Slc39a6^tm1Tfk
Targeted Allele Detail

Summary

• Symbol: Slc39a6^tm1Tfk
• Name: solute carrier family 39 (metal ion transporter), member 6; targeted mutation 1, Toshiyuki Fukada
• MGI ID: MGI:6112647
• Gene: Slc39a6 Location: Chr18:24712938-24736874 bp, - strand Genetic Position: Chr18, 13.18 cM
• Alliance: Slc39a6^tm1Tfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254216
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic region including all of exons 3 and 4 was replaced with a neo cassette in inverse orientation. (J:254216)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc39a6 Mutation: 39 strains or lines available

References

• Original: J:254216 Bin BH, et al., Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12243-12248
• All: 1 reference(s)