Mrln^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Mrln^tm1.1Nju
• Name: myoregulin; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6113278
• Gene: Mrln Location: Chr10:70040494-70055541 bp, + strand Genetic Position: Chr10, 36.68 cM, cytoband B5.2
• Alliance: Mrln^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243999
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was floxed and removed by cre-mediated recombination along with the FRT-flanked neomycin resistance cassette. RT-PCR confirmed the bsence of transcript expression in muscles. (J:243999)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrln Mutation: 4 strains or lines available

References

• Original: J:243999 Yu X, et al., Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD. Nat Commun. 2017 Jan 16;8:14016
• All: 2 reference(s)