Ltbr^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ltbr^m2Btlr
• Name: lymphotoxin B receptor; mutation 2, Bruce Beutler
• MGI ID: MGI:6113397
• Synonyms: armitage
• Gene: Ltbr Location: Chr6:125283534-125290848 bp, - strand Genetic Position: Chr6, 59.32 cM
• Alliance: Ltbr^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 125,312,794 on chromosome 6, corresponding to base pair 1,077 in GenBank genomic region NC_000072. The mutation corresponds to residue 636 in the mRNA sequence NM_010736 within exon 4 of 10 total exons. The mutation results in an arginine to tryptophan substitution at position 146 (R146W) in the protein. (J:254823)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ltbr Mutation: 47 strains or lines available

References

• Original: J:254823 Choi JH, et al., Mutagenetix entry for armitage. MGI Direct Data Submission. 2018
• All: 1 reference(s)