Cd22^m5Btlr
Chemically induced Allele Detail

Summary

• Symbol: Cd22^m5Btlr
• Name: CD22 antigen; mutation 5, Bruce Beutler
• MGI ID: MGI:6113421
• Synonyms: rain
• Gene: Cd22 Location: Chr7:30564829-30579767 bp, - strand Genetic Position: Chr7, 19.26 cM
• Alliance: Cd22^m5Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to G transition at base pair 30,877,534 (v38) on chromosome 7, or base pair 2,808 in the GenBank genomic region NC_000073. The mutation corresponds to residue 709 in the mRNA sequence NM_001043317 (variant 1) within exon 5 of 16 total exons and to residue 584 in the mRNA sequence NM_009845 (variant 2) within exon 3 of 14 total exons. The mutated nucleotide is indicated in red. The mutation results in an isoleucine to threonine substitution at position 116 (I116T) in both isoforms of the protein. (J:254827)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd22 Mutation: 64 strains or lines available

References

• Original: J:254827 Zhong X, et al., Mutagenetix entry for rain. MGI Direct Data Submission. 2018
• All: 1 reference(s)