Stat1^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Stat1^m3Btlr
• Name: signal transducer and activator of transcription 1; mutation 3, Bruce Beutler
• MGI ID: MGI:6113472
• Synonyms: rollo
• Gene: Stat1 Location: Chr1:52158599-52201024 bp, + strand Genetic Position: Chr1, 26.81 cM
• Alliance: Stat1^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to A transversion at base pair 52,153,923 (v38) on chromosome 1, or base pair 34,486 in the GenBank genomic region NC_000067. The mutation corresponds to residue 2,270 in the mRNA sequence NM_001205313 within exon 22 of 25 total exons. The mutation results in substitution of tyrosine 651 for a premature stop codon (Y651*) in the protein. (J:254835)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat1 Mutation: 74 strains or lines available

References

• Original: J:254835 Nair-Gill E, et al., Mutagenetix entry for rollo. MGI Direct Data Submission. 2018
• All: 1 reference(s)