Trp53bp1^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Trp53bp1^m4Btlr
• Name: transformation related protein 53 binding protein 1; mutation 4, Bruce Beutler
• MGI ID: MGI:6113496
• Synonyms: verily
• Gene: Trp53bp1 Location: Chr2:121023762-121101888 bp, - strand Genetic Position: Chr2, 60.37 cM
• Alliance: Trp53bp1^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU treatment induced a T-to-A transversion at base pair 121,211,313 (GRCm38) on chromosome 2, or base pair 79,013 in the GenBank genomic region NC_000068. The mutation corresponds to residue 3,890 in the mRNA sequence NM_013735 within exon 18 of 28 total exons. The mutation results in substitution of valine 1254 with an aspartic acid (p.V1254D) in the protein. (J:254852)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trp53bp1 Mutation: 100 strains or lines available

References

• Original: J:254852 Choi JH, et al., Mutagenetix entry for verily. MGI Direct Data Submission. 2018
• All: 1 reference(s)