Card11^M4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Card11^M4Btlr
• Name: caspase recruitment domain family, member 11; mutationn 4, Bruce Beutler
• MGI ID: MGI:6113504
• Synonyms: Dealer
• Gene: Card11 Location: Chr5:140858745-140986337 bp, - strand Genetic Position: Chr5, 79.42 cM
• Alliance: Card11^M4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced to G transition at base pair 140,885,877 (v38) on chromosome 5, or base pair 114,720 in the GenBank genomic region NC_000071. The mutation corresponds to residue 2,389 in the mRNA sequence NM_175362 within exon 16 of 25 total exons. The mutation results in a serine to glycine substitution at position 690 (S690G) in the protein. (J:254856)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card11 Mutation: 59 strains or lines available

References

• Original: J:254856 Zhong X, et al., Mutagenetix entry for Dealer. MGI Direct Data Submission. 2018
• All: 1 reference(s)