Pik3r1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pik3r1^m1Btlr
• Name: phosphoinositide-3-kinase regulatory subunit 1; mutation 1, Bruce Beutler
• MGI ID: MGI:6113575
• Synonyms: anubis
• Gene: Pik3r1 Location: Chr13:101817269-101904725 bp, - strand Genetic Position: Chr13, 53.92 cM
• Alliance: Pik3r1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Modified isoform(s))
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 101,702,776 (v38) on chromosome 13, or base pair 65,442 in the GenBank genomic region NC_000079. The mutation corresponds to residue 1,188 in the mRNA sequence NM_001077495 within exon 5 of 16 total exons. The mutation results in a substitution of tyrosine 189 to a premature stop codon (Y189*) in the p85alpha protein; p55alpha and p50alpha are not affected. (J:254890)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pik3r1 Mutation: 56 strains or lines available

References

• Original: J:254890 SoRelle J, et al., Mutagenetix entry for anubis. MGI Direct Data Submission. 2018
• All: 1 reference(s)